Επιστημονικές δημοσιεύσεις



  1. Karavasilis A, Karkalousos P, Trapali M, Founztoula C, Karikas GA. Destabilization of HIF-1a by Diabetes, Oxidative
    Stress, Obesity and Other Related Disorders, Journal of Diabetes Mellitus, May 2023
  2. Mazarakis A, Tsotsou GE. Smartphone-based colourimetric detection of analytes after pre-concentration onto a hectorite clay-hydroxyethylcellulose hybrid, Research Square, https://doi.org/10.21203/rs.3.rs-2631527/v1
  3. Καρίκας ΓΑ. Κανναβιδιόλη: Πρόσφατα φαρμακοδυναμικά δεδομένα; Φαρμακευτικός κόσμος, 10/4/2023, https://www.farmakeutikoskosmos.gr
  4. Καρίκας ΓΑ. Κάνναβη και συμπληρώματα διατροφής;. Φαρμακευτικός κόσμος, 10/2/2023, https://www.farmakeutikoskosmos.gr
  5. Konstantopoulou E, Trapali M. Verbal Dyspraxia: A Case Study. Open Journal of Preventive Medicine, 2023, 13, 1-10
  6. Papounidis L, Trapali M. The Application of Honeybee Products in the Health Sector, Advances in Biological Chemistry 2023: Advances in Biological Chemistry, 2023, 13, 1-16, DOI: 10.4236/abc.2023.131001 
  7. Tsotsou GE, Mazarakis AP. Prospects and limitations of a clay-enabled pre-concentration method for spectrophotometric quantification, Applied Clay Science 233 (2023), https://doi.org/10.1016/j.clay.2023.106829
  8. Πρέτσι, Ν, Καρκαλούσος Π. Εκπαίδευση πρωτότοκων μητέρων στη φροντίδα νεογνών μέσω ασύγχρονης μάθησης. Το βήμα του Ασκληπιού, Ιανουάριος -Μάρτιος 2023, Τομ 22(1):55-71
  9. Liatsopoulou A., Varvaresou A., Mellou F., Protopapa E., Iontophoresis in dermal delivery. A review of applications in dermatocosmetic and aesthetic sciences. International Journal of Cosmetic Science https://onlinelibrary.wiley.com/doi/epdf/10.1111/ics.12824




  1. Tsotsou GE, Potiriadi I, A UV/Vis spectrophotometric methodology for quality control of stevia-based extracts in the food industryFood Control 137, 108932
  2. Tsotsou GE, Mavroeidis P, Georgiou JS, Adsorption onto hybrid hectorite-hydroxyethyl cellulose composite as a pre-concentration method for the spectrophotometric quantification of a cationic organic molecule, irinotecan, Applied Clay Science 230, 106694
  3. Kalyvas N, Saatsakis G, Valais I,  Fountzoula C, Ninos K, Sianoudis I, Bakas A, Fountos G, Ioannis Kandarakis I, George Panayiotakis G, Michail C, Study of UV interactions on PMMA based ZnCuInS/ZnS quantum dot films, Optical Materials, Volume 129, July 2022, 112493
  4. De Martinis Α, Montalto L, Calise L, Rinaldi D, Mengucci P, Michail C, Fountos G, Martini N, Koukou V, Valais I, Bakas A, Fountzoula C, Kandarakis I, David S, Luminescence and Structural Characterization of Gd2O2S Scintillators Doped with Tb3+, Ce3+, Pr3+ and F for Imaging Applications, Crystals 202212(6), 854; https://doi.org/10.3390/cryst12060854
  5. Σαρικαβάζης Ν, Καρκαλούσος Π. Η μεταβολική ακαμψία ως φαινόμενο των καιρών, η μεταβολική ευελιξία και η δράση της AMPK. Δελτίο Ελληνικής Εταιρείας Κλινικής Χημείας – Κλινικής Βιοχημείας, Μάρτιος 2022
  6. Δημουλάς Ε, Τράπαλη Μ. Βαρβιτουρικά: Δράση, Ενδείξεις & Αντενδείξεις, Τοξικότητα και Ανίχνευση, Δελτίο Ελληνικής Εταιρείας Κλινικής Χημείας – Κλινικής Βιοχημείας, Μάρτιος 2022
  7. Vourtsis, D, Papageorgiou E, Kriebardis A, Karikas GA,  Van Willigen G, Karkalousos P, A swift risk analysis for COVID-19 testing facilities using rapid tests, Vol 3, Issue 4, 2022
  8. Diareme M, Kardari A, Trapali M, Karkalousos P, Metabolic Response of Diabetic Patients with Obesity and No Obesity during Bruce Treadmill Test, 10.4236/jdm.2022.124016, Journal of Diabetes Mellitus, 2022, 12, 204-215
  9. Myrto Chatzigianni M, Pavlou P, Siamidi A, Vlachou M, Varvaresou A, Papageorgiou S. Environmental impacts due to the use of sunscreen products. Ecotoxicology https://doi.org/10.1007/s10646-022-02592-w
  10.  Dimitris Matiadis D, Fountzoula C, Trapali M, Karkalousos P, Sagnou M. Naked-eye colorimetric cyanide detection by monocarbonyl analogue of curcumin. Journal of Molecular Structure 2022, 1268,1-9.  https://doi.org/10.1016/j.molstruc.2022.133677
  11. Dogkas N, Τrapali M, Fountzoula C, Karikas GA, Karkalousos P. Serum Lipids and Lipokines as Prognostic/Diagnostic Biomarkers in Common Cancers. Journal of Diabetes Mellitus 2022, 12, 122-140. https://doi.org/10.4236/jdm.2022.122011
  12. Roumelioti E, Karkalousos P, Trapali M. Dietary supplements: innocent or potentially carcinogenic? Review clinical pharmacology and pharmaconetics 2022 36(1): 5-10.
  13. Papadopoulou,A., Karkalousos, P. and Trapali, M. Effects of Diabetes Mellitus upon Sperm Quality Insight into Molecular Level. Journal of Diabetes Mellitus 2022, 12, 75-86. https://doi.org/10.4236/jdm.2022.122008
  14. Vlassopoulos G, Karikas G, A. Papageorgiou E, Psaromiligos G, Giannouli N, Karkalousos P. Vocational High Schools Apprenticeship Program, in Greece: Application, Recent Facts and Views. Open Journal of Leadership > Vol.11 No.1, March 2022
  15. Papadopoulos A., Assimomytis N. and Varvaresou A. Sample Preparation of Cosmetic Products for the Determination of Heavy Metals Cosmetics 9 :21 https://doi.org/10.3390/cosmetics9010021 (2022).
  16. Trapali V, Karikas GA, Papageorgiou Ε, Fountzoula C, Trapali M, Karkalousos P,The Use of Common E-Learning Tools towards State (Degree) of Scientific Literacy in Greek Second Chance Schools (SCS), during the First Wave of the COVID-19 Pandemic,  Creative Education 2022, 13, 167-182. https://doi.org/10.4236/ce.2022.131012



  1. Grafakou ME, Barda C, Karikas GA, Heilmann J, Skaltsa H. Cajamolides A-N: Cytotoxic and anti-inflammatory sesquiterpene lactones from Calea jamaicensis. Bioorg Chem. 2021 Nov;116:105351. doi: 10.1016/j.bioorg.2021.105351
  2. Pavlou P, Siamidi A, Varvaresou A, Vlachou M. Skin Care Formulations and Lipid Carriers as Skin Moisturizing Agents. Cosmetics 2021, 8, 89. https:// doi.org/10.3390/cosmetics8030089
  3. Pafili A, Meikopoulos T, Kontogiannidou E, Papageorgiou S, Demiri E, Meimari D, Fatouros D, Gika H, Theodoridis G, Development and validation of LC-MS/MS method for the determination of UV-filters across human skin in vitro, Journal of Chromatography B  Volume 1167, 15 March 2021, 122561
  4. Anagnosti L, Varvaresou A, Pavlou P, Protopapa E, Carayanni V. Worldwide actions against plastic pollution from microbeads and microplastics in cosmetics focusing on European policies. Has the issue been handled effectively? , Marine Pollution Bulletin 162 (2021) 
  5. Shariare MH, Parvez MAK, Karikas GA, Kazi M. The growing complexity of COVID-19 drug and vaccine candidates: challenges and critical transitions. J Infect Public Health. 2020 Dec 15;14(2):214-220. doi: 10.1016/j.jiph.2020.12.009
  6. Vlassopoulos G, Karikas GA, Papageorgiou E, Psaromiligos G. Giannouli N, Karkalousos P. Αssessment of Greek High School Students towards Distance Learning, during the First Wave of COVID-19 Pandemic. Creative Education, 2021, 12, 934-949
  7. Μαρόζικ Λ, Karkalousos P. To πυρηνικό ατύχημα του Τσερνόμπιλ 35 χρόνια και οι επιπτώσεις του ως παγκόσμιο πρόβλημα υγείας. Ενημερωτικό δελτίο ΕΕΚΧ-ΚΒ. Μάρτιος 2021
  8. Τράπαλη Β, Φούντζουλα Χ, Παπαγεωργίου Ε, Τράπαλη Μ, Καρκαλούσος Π. H πρόκληση της τηλεκπαίδευσης στα σχολεία Δεύτερης Ευκαιρίας: Μελέτη περίπτωσης στο σχολείο Δεύτερης Ευκαιρίας Πύργου στο εκτός έδρας τμήμα Αμαλιάδας. Οι εκπαιδευτικοί στο προσκήνιο. Τεύχος 37 (5/2021): 47-54.
  9. Σταμούλη Μ, Μουρτζίκου Α, Καρκαλούσος Π. Κριτήρια που διαμορφώνουν τους στόχους ποιότητας σε ένα κλινικό εργαστήριο. Αρχεία Ελληνικής Ιατρικής 2021, 38(3):305-312
  10.  Varvouni EF, Chinou I. Karikas G.A. Is Portulaca olearacea a medicinal plant? Overview of recent data. Pharmakeftiki, 33(I), 30-51, (2021)
  11.  Vukicevic P, Klisic A, Kotur J, Mikic A, Bogavac-Stanojevic, Matkovic M, Putnic S, Aleksic N, Tutus V, karikas G.A. Paraoxonase1 low activity and SYNTAX score may predict postoperative complications after coronary artery surgery. European Review for Medical and Pharmacological Sciences 2021, 25:1511-1521, doi: 10.26355/eurrev_202102_24858
  12. Pavlou P, Siamidi A, Vlachou M, Varvaresou A. UV Filters and Their Distribution on the Skin through Safe, Non-Penetrating Vehicles. J. Cosmet. Sci., 72, 298–324 (May/June 2021)
  13. Raikou V, Kalogria E, Varvaresou A, Tsirivas E, Panderi, I. Quantitation of Acetyl Hexapeptide-8 in Cosmetics by Hydrophilic Interaction Liquid Chromatography Coupled to Photo Diode Array Detection. Separations 2021, 8, 125. doi: 10.3390/separations8080125
  14. Kreatsoula A, Trapali M (2021). Periostin and cancer. Review of clinical pharmacology and pharmacokinetics, 35(1), 5-14
  15. Βρετού Μ, Τράπαλη Μ (2021) Η δράση της Βιταμίνης D σε Ασθενείς με Πολλαπλή Σκλήρυνση, Επιθεώρηση κλινικής φαρμακολογίας και φαρμακοκινητικής, 39(1),11-20
  16. Trapali Μ, Lagouri V (2021). Vasculoprotective and Neuro-protective Effects of Various Parts of Pomegranate: In Vitro, In Vivo, and Preclinical Studies [Online First], Intech Open, DOI: 10.5772/intechopen.96680. Available from: https://www.intechopen.com/online-first/vasculoprotective-and-neuroprotective-effects-of-various-parts-of-pomegranate-in-vitro-in-vivo-and-p
  17. Trapali Μ (2021). Biomarkers of aging, a mini review, Review of clinical pharmacology and pharmacokinetics, 35(2),55-58
  18. Voyiatzaki C, Orovas C, Trapali M, Chaniotis D, Kriebardis A, Beloukas A,  Thalassinos N, Orovou E, Iatrakis G, Antoniou E (2021) Toxoplasmosis Screening During Pregnancy. A Systematic Review, Acta Inform Med 2021; 29-3: 216-223 DOI: 10.5455/aim.2021.29.216-223
  19. Τράπαλη Μ (2021). Η Εμπλοκή του Παράγοντα Ενεργοποίησης Αιμοπεταλίων (PAF) σε διαφορές Ασθένειες, Επιθεώρηση Κλινικής Φαρμακολογίας και Φαρμακοκινητικής 39(1), 29-34
  20. Halvatsiotis A, Siatelis P, Koulouvaris D, Vougiouklaki E, Routsi M, Papapanou M, Trapali M, Houhoula D (2021), Correlation of polymorphism of Q223R Leptin Receptor with the expression of Leptin gene in Greek Student volunteers (2021) AIMS Medical Science, 8(4): 301–310. DOI: 10.3934/medsci..2021025
  21. Trapali Μ (2021). Oxidic degradation of lipids in patients with type II diabetes, Review of clinical pharmacology and pharmacokinetics, 35(2),75-77
  22. Trapali M (2021). Effects of Sibutramine Treatment on Serum Lipoproteins and Il-6 Levels in Rats Fed with High Protein Diet, Nov Res Sci. 8(1). NRS. 000680 DOI: 10.31031/NRS.2021.08.000680
  23. Bourkoula A, Konsta E, Papadopoulou A, Trapali M (2021). Lipidic classes involved in Diabetes mellitus, Nov Res Sci. NRS. 000685. 2021. 
  24. Trapali Μ (2021). Ellagic Acid and Type 2 Diabetes, JOJ Nurse Health Care, 12(1) DOI: 10.19080/JOJNHC.2021.12.555829


  1. Tsotsou GE, Gkotzamani P, Petro V, Argyropoulou A, Karkalousos P. A Simple, Rapid and Low-Cost Spectrophotometric Method for Irinotecan Quantification in Human Plasma and in Pharmaceutical Dosage Forms. The analytical methods. The Royal Society of Chemistry. DOI: 10.1039/D0AY02201B
  2. Mellou F, Varvaresou A, Papageorgiou S, Protopapa E, Liatsopoulou. E. Papain: an enzyme of multiple applications. Review of Clinical pharmacology and Pharmacokinetics. Υπό δημοσίευση.
  3. Ράικου B, Kίντζιου E, Bαρβαρέσου A, Γαρδίκη B, Δηλαβέρη Α. Βιολογικά οφέλη από τη χρήση της ιαματικής λάσπης. Review of Clinical pharmacology and Pharmacokinetics. Υπό δημοσίευση.
  4. Papageorgiou S, A. Varvaresou Α, Panderi Ι, Giannakou M, Spiliopoulou C, Athanaselis S. Development and validation of a reversed-phase high- performance liquid chromatographic method for the quantitation and stability of a-lipoic acid in cosmetic creams  International Journal of Cosmetic Science, Vol 21, pp 221-228, 2020 
  5. Gkouskou H, Vlastos I, Karkalousos P, Chaniotis D, Sanoudou D, Eliopoulos A. The Virtual Digital Twins concepth in Precision Nutrition. Advances in Nutrition, 2020.
  6. Athanasiadou Z, Mourtzikou A, Stamouli M, Karkalousos P, Athanasiadou Z, Marasidi E, Skiris A. Quality Indicators for the Performance Evaluation at a Biochemistry Laboratory: QIs for a Biochemistry Laboratory. International Journal of Reliable and Quality E-Healthcare (IJRQEH) 9(2).
  7. Τσότσου ΓΕ, Ποτηριάδη Ι, Καρκαλούσος Π. Φωτομετρική μέθοδος ποσοτικού προσδιορισμού γλυκοζιτών της στεβιόλης σε εμπορικά
    δείγματα. ΕΕΚΧ-ΚΒ, Ενημερωτικό δελτίο Τεύχος 35, Σεπτέμβριος 2020.
  8. Saatsakis G, Michail C, Fountzoula C, Bakas A, Kalyvas N, Bakas A, Ninos K, Fountos G, Kandarakis I, Valais I, Panayiotakis G.  Poly (Methyl Methacrylate) Structure Modification through Zn-Cu-In-S/ZnS Quantum Dot Nanocrystals Dispersion., Procedia Structural Integrity 25, 47-54.
  9. Σιαμούλη Μ, Μουρτζίκου Α, Καρκαλούσος Π. Κριτήρια που διαμορφώνουν τους στόχους ποιότητας στο κλινικό εργαστήριο,  Archives of Hellenic Medicine 2021, 38(3):305–312
  10. Trapali M (2020). Pregnancy and Carbohydrate Metabolism Short Communication, JO Nursing and Health Care, 11(5) DOI: 10.19080/JOJCS.2020.11.555825
  1. Mellou F, Varvaresou A, Papageorgiou S. Renewable sources: Applications in personal care formulations. International Journal of Cosmetic Science 41: 517-525 
  2. Varvaresou A., Iakovou K., Mellou F., Myrogiannis D, Papageorgiou S., Targeted Therapy in oncology patients and skin: Pharmaceutical and dermocosmetic management. Journal of Cosmetic Dermatology 1-7,  DOI: 10.1111/jocd.13211
  3. Καλογριά E., Βαρβαρέσου Α, Πρωτόπαπα Ε, Παντέρη Ι. Αντιιδρωτικά προϊόντα και αργίλιο. Φαρμακευτική 31: 3 (2019), 113-123
  4. Karistinou S. Varvaresou A. Mellou F. Nanoparticles and topical application of active ingredients. Epitheorese Klinikis Farmakologias kai Farmakokinetikis 37(3): 183-198
  5. Stamouli M, Mourtzikou A, Karkalousos P, Athanasiadou Z, Marasidi E, Skiris A.  Application of Failure Modes and Effects Analysis (FMEA) During the Pre-analytical Phase in a Greek Biochemistry Laboratory International Journal of Reliable and Quality E-Healthcare (IJRQEH) 8(3).
  6. Triantafyllou A, Farmakis D, Lampropoulos Κ, Karkalousos P, Triantafyllou E, Papingiotis G, Megalou A, Karpanou E, Impact of β-thalassemia trait carrier state on inflammatory status in patients with newly diagnosed hypertension, May 2019; 20/5: 284-9.
  7. Saatsakis G,Michail C, Fountzoula C, Kalyvas N, Bakas A, Nikos K, Fountos G, Sianoudis I, Kandarakis I, Panayiotakis GS, Valais I. Fabrication and Luminescent Properties of Zn–Cu–In–S/ZnS Quantum Dot Films under UV Excitation. Applied Sciences 9 (11), 2367.
  8. Saatzakis G, Kalyvas N, Michail C, Ninos K, Bakas A, Fountzoula C, Sianoudis I, Karpetas G, Fountos G, Kandarkis I, Valais I, Panayiotakis G. Optical Characteristics of ZnCuInS/ZnS (Core/Shell) Nanocrystal Flexible Films Under X-Ray Excitation. Crystals 9 (7), 343.
  9. Nikolopoulos D, Valais I, Yannakopoulos P, Michail C, Fountzoula C, Bakas A, Kandarakis I, Panayiotakis G. Luminescence Efficiency of Cadmium Selenide/Zinc Sulfide (CdSe/ZnS) Quantum Dot Nanoparticle Sensors Under X-Ray Excitation, Nuclear Radiation Nanosensors and Nanosensory Systems pp 53-59.
  10. Τεσσερομμάτη Χ, Καρίκας ΓΑ. Χημεία και φαρμακοτοξικότητα της κάνναβης: Σύγχρονες απόψεις. Φαρμακευτική 31: 3 (2019), 126 -156.
  11.  Soura E., Karikas, G.A. Acute myeloid leukaemia: recent data on prognostic gene mutations, in relation to stratified therapies for elederly patients. BUON 24(4): 1326-1339, (2019)